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Friday 4 April 2014

PHARMACOLOGY PAPER 2-MARCH 2014-2ND MBBS-KUHS



Q.P. Code: 202001                     Reg. no.: …………………
Second Professional MBBS Degree Examinations, March 2014
Pharmacology- Paper II

Time: 2 Hours                              Total Marks: 40

        Answer all questions
        Draw diagrams wherever necessary

Essays: (2x6=12)

1.      Enumerate the antibiotics which act by inhibiting cell wall synthesis. Mention the detailed mechanism of action of any one of them on bacterial cell wall synthesis. Add a note on beta lactamase inhibitors
(2+2+2=6)
       2.    Read the clinical problem and answer the following questions: 40 years old man who was on   
              metronidazole for amoebic dysentery went to a cocktail party where he consumed alcohol. After 
              some time, he started developing symptoms like flushing, burning sensation, throbbing head ache, 
              dizziness, tightness in chest, vomiting.

  • What is the reason for his symptoms
  • What are the other uses of metronidazole
  • What are the adverse effects produced by metronidazole (2+2+2=6)

Short notes: (5x3=15)

3.      Alpha glucosidase inhibitors
4.      Serious adverse effects produced by contraceptive pills
5.      Azithromycin
6.      Vinca alkaloids
7.      Proton pump inhibitors
Answer briefly: (5x1=5)
8.      Radical cure in plasmodium vivax infection
9.      Drug used in thyrotoxic crisis
10.   Super ORS
11.   Adverse effects of metoclopramide
12.   Antiseptics


Name two drugs for: (8x1=8)  

13.   Topical antifungals
14.   Anti pseudomonal drugs
15.   H2 blockers
16.   Calcineurin inhibitors
17.    Fluoroquinolones
18.   Selective estrogen receptor modulators
19.   First line anti tubercular drugs
20.   Bisphosphonates