BIOCHEMISTRY PAPER 2-1ST MBBS KUHS-AUGUST 2014

Q.P.Code:106001                                             Reg.no:…………….

First professional MBBS Degree Examinations, August 2014

BIOCHEMISTRY-PAPER II

Time: 3Hours                                           Total Marks:50

• Answer all questions
• Draw diagrams wherever necessary

Essay (10)

1. Define replication. Describe in detail the replicative process in prokaryotes with the help of diagrams

 (1+6+3=10)

Short essays (2×5=10)

2. Discuss the structure and functions of immunoglobulins

3. Discuss the co-enzyme role of thiamine and the deficiency disorder

Short notes (5×3=15)

4. Differences between metabolic acidosis and respiratory acidosis

5. PCR technique

6. Blood and urinary findings in various types of jaundice

7. List the functions of selenium

8. Frame shift mutation

Answer briefly (5×2=10)

9. Calcitriol

10. Congenital erythropoietic porphyria

11. Wobble hypothesis

12. Spliceosomes

13. Define renal clearance*/Creatinine clearance**

Give precise answers (5×1=5)

14. Mention the normal serum albumin level and list two conditions where serum albumin is decreased

15. Mention any two features of p53 gene

16. How glycine is used in detoxification reactions

17. Enumerate the functions of zinc in the body

18. Name the amino acids involved in the synthesis of pyramidine

*Question changed

**New question