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Monday 1 December 2014

PHARMACOLOGY PAPER 1-2ND MBBS KUHS-SEPTEMBER 2014



Q.P. Code: 201001                     Reg. no.: …………………
Second Professional MBBS Degree Examinations, September 2014
Pharmacology- Paper I

Time: 2 Hours                              Total Marks: 40

        Answer all questions
        Draw diagrams wherever necessary

Essays: (2x6=12)

1.      Classify beta blockers with one example for each. Mention the therapeutic uses and adverse effects of propranolol (2+2+2=6)


2.      Read the case history and answer the following questions. Mr. George aged 45 years was on maintenance dose of warfarin 5 mg/day for his ischemic heart disease. Subsequently he developed joint pains for which he was administered tab. Aspirin 300 mg thrice daily after food. One week later he was brought to casualty in a state of shock due to severe haemetemesis.

  • How will you explain haematemesis in tis patient
  • How it could have been prevented
  • How will you treat the present emergency?(2+2+2=6)


Short notes: (5x3=15) 

3.      Propofol
4.      Dopamine
5.      Ramipril
6.      Treatment of organophosphorous poisoning
7.      Mention SSRI and its advantages 

Answer briefly: (5x1=5)
8.      Rationale for the use of adrenaline along with local anesthetics
9.      Two uses and two adverse effects of calcium channel blockers
10.   Mechanism of action of dantrolene sodium
11.   Rationale for the use of nitrates in angina pectoris
12.   Chemical antagonism with one example


Name two drugs for:  (8x1=8)


13.   Drugs administered by inhalation route
14.   Anaphylactic shock
15.   Hypertensive emergencies
16.   Pre-anesthetic medication
17.   Treatment of migraine
18.   Supra ventricular tachycardia
19.   Benign prostatic hypertrophy
20.   Cerebral edema