Q.P. Code: 202001 Reg. no.: …………………
Second Professional MBBS Degree Examinations, September 2014
Pharmacology- Paper II
Time: 2 Hours Total Marks: 40
•
Answer all questions
•
Draw
diagrams wherever necessary
Essays: (2x6=12)
1. Classification
of fluoroquinolones. Describe the mechanism of action, therapeutic uses and
adverse effects of sparfloxacin. (2+2+2=6)
2. Read the
case history and answer the following questions. Mr. Raman 32 years has
developed severe epigastric pain after taking tab. Ibuprofen 400 mg tds for his
joint pain
- Mention two drugs used in NSAID induced gastric ulceration
- Mechanism of action of proton pump inhibitors
- Drugs for eradication of H.pylori infection
Short notes:
(5x3=15)
3. Bisphosphonates
4. Adverse
effects of aminoglycosides
5. Anti thyroid
drugs
6. Rifampicin
7. Taxanes in
cancer chemotherapy
Answer
briefly: (5x1=5)
8.
Two uses and two adverse effects of oral contraceptive pills
9.
Mechanism of action of meoclopromide
10.
Two advantages of human insulin
11.
Specify the important spectrum of vancomycin
12.
Rationale of estrogen in hormone replacement therapy
|
|
Name two
drugs for: (8x1=8)
|
13. Chloroquine
resistant malaria
14. Urinary
tract infections
15. Immunosuppressive
in organ transplantation
16. Irritable
bowel syndrome
17. Gram negative
septicemia
18. Tocolytics
19. Aromatase
inhibitors
20. Retro viral
infections
